1414972-27-2Relevant academic research and scientific papers
Facile and mild displacement of nitrite ions in electron-deficient nitroarenes by alkyl or aryl thiols in the presence of magnesium methoxide as a solid base catalyst
Naeimi, Hossein,Moradian, Mohsen
, p. 2223 - 2226 (2012)
The nucleophilic aromatic substitution reaction (Sr) between nitroarenes (having electron-withdrawing groups in the ortho or para position), and alkyl- or arylthiols using magnesium methoxide as a solid base catalyst is described. This method leads to the creation of a series of valuable compounds from arylsulfides via nucleophilic displacement of the nitro group with the sulfanyl moiety. This facile method is a synthetically useful process, and it is significant that the nucleophile is promoted effectively by magnesium methoxide as a base in N,N-dimethylformamide. The displacement of then nitrite ion occurred in the presence of a variety of functional groups that caused an electron-deficient ring such as aldehyde, ketone, ester, cyano, and nitro groups. Georg Thieme Verlag Stuttgart ? New York.
