14150-64-2Relevant articles and documents
Slyusarenko,I.S. et al.
, (1976)
Synthesis method of ethyl hydrazinoacetate hydrochloride
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Paragraph 0015; 0018; 0021; 0024; 0027; 0030, (2019/01/23)
The invention discloses a synthesis method of ethyl hydrazinoacetate hydrochloride and belongs to the technical field of organic synthesis. The technical scheme is characterized in that chloroacetic acid is used as an initial material to react with hydrazine hydrate to produce intermediate hydrazine acetic acid, hydrazine acetic acid and ethanol form ester to obtain ethyl hydrazinoacetate, a hydrogen chloride solution is added to react to obtain a crude product of ethyl hydrazinoacetate hydrochloride, and high-purity ethyl hydrazinoacetate hydrochloride is obtained through refinement. The method has the advantages of being mild in reaction condition, high in yield, high in purity, low in cost, economical, environmentally friendly, applicable to industrialization and the like and is a synthesis method with industrial production values.
Solution phase synthesis of imidazo[1,2-b]pyrazol-2-one, an interesting 5,5-fused heterocyclic ring system
Blass, Benjamin E.,Srivastava, Anil,Coburn, Keith R.,Faulkner, Amy L.,Janusz, John J.,Ridgeway, James M.,Seibel, William L.
, p. 619 - 621 (2007/10/03)
The solution phase synthesis of a series of imidazo[1,2-b]pyrazol-2-ones, a fused 5,5-ring system, based on diverse set of hydrazino acids and malononitriles is described. The method involves formation of 5-aminopyrazoles followed by intra-molecular cyclodehydration.
