503-68-4Relevant academic research and scientific papers
Cyclic amino acids and derivatives thereof useful as pharmaceutical agents
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, (2008/06/13)
The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.
2-Substituted thio-6-substituted-carbapen-2-em-3-carboxylic acids
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, (2008/06/13)
Disclosed are 2-substituted thio-6-substituted-carbapen-2-em-3-carboxylic acids (I) and their pharmaceutically acceptable salt, ester and amide derivatives which are useful as antibiotics: STR1 wherein: R5 is CN, STR2 (R is alkyl or aryl); R6 is hydrogen, R5, alkyl, aryl or heteroaryl; and R7 and R8 are, inter alia, hydrogen, alkyl, alkenyl, aryl and aralkyl.
