1415022-92-2Relevant articles and documents
Synthesis and biological evaluation of new fluorine substituted derivatives as angiotensin II receptor antagonists with anti-hypertension and anti-tumor effects
Da, Ya-Jing,Yuan, Wei-Dong,Xin, Ting,Nie, Yong-Yan,Ye, Ying,Yan, Yi-Jia,Liang, Li-Sha,Chen, Zhi-Long
, p. 7101 - 7111 (2013/01/15)
The synthesis and pharmaceutical activity of new potent non-tetrazole angiotensin II (Ang II) receptor antagonists were described. These compounds were fluorine substituted derivatives of Losartan, Valsartan and Irbesartan with carboxylic acid group as re