1415045-31-6

Basic information

• Product Name: N,N-diethyl-3-(4-fluorophenyl)pyrazine-2-carboxamide
• CAS NO: 1415045-31-6
• Molecular Weight: 273.31
• Mol File: 1415045-31-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N-diethyl-3-(4-fluorophenyl)pyrazine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-3-(4-fluorophenyl)pyrazine-2-carboxamide(1415045-31-6)
• EPA Substance Registry System: N,N-diethyl-3-(4-fluorophenyl)pyrazine-2-carboxamide(1415045-31-6)

Safety Data

• Hazardous Substances Data: 1415045-31-6(Hazardous Substances Data)

Upstream product

• 98-97-5 2-pyrazylcarboxylic acid 
• 19847-10-0 pyrazinoyl chloride 
• 1765-93-1 4-fluoroboronic acid 
• 18960-18-4 N,N-diethylpyrazine-2-carboxamide 
• 225916-39-2 2-(4-fluorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane 

Relevant articles and documents

C-H activation by amide chelation control: Ruthenium-catalyzed direct synthesis of 2-Aryl-3-furanamides

A new, catalytic methodology for the synthesis of heterobiaryls by the ruthenium-catalyzed C-H activation/cross-coupling of heterocyclic amides with aryl boroneopentylates is surveyed. From this survey, the highly regioselective reaction of furan-3-carboxamide to give 2-aryl-3-furanamides is optimized and generalized in scope with respect to the aryl boroneopentylate coupling partners. Established thereby is a one-step synthetic method which may supercede the broadly applied two-step directed ortho metalation (DoM)-cross coupling reaction involving cryogenic and strong base conditions and which has potential for further ortho and remote metalation chemistry.