1415124-96-7

Basic information

• Product Name: 2,6-dichloro-4-(hydroxymethyl)benzoic acid
• Synonyms: 2,6-dichloro-4-(hydroxymethyl)benzoic acid
• CAS NO: 1415124-96-7
• Molecular Weight: 221.04
• Mol File: 1415124-96-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,6-dichloro-4-(hydroxymethyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dichloro-4-(hydroxymethyl)benzoic acid(1415124-96-7)
• EPA Substance Registry System: 2,6-dichloro-4-(hydroxymethyl)benzoic acid(1415124-96-7)

Safety Data

• Hazardous Substances Data: 1415124-96-7(Hazardous Substances Data)

Upstream product

• 1415124-95-6 methyl 2,6-dichloro-4-(hydroxymethyl)benzoate 
• 264276-14-4 dimethyl 2,6-dichlorobenzene-1,4-dicarboxylate 
• 5372-81-6 dimethyl aminoterephthalate 
• 1258298-04-2 2-amino-3,5-dichloro-4-(carbomethoxy)benzoic acid methyl ester 

Downstream Products

• 1415123-73-7 N-{1-[2,6-dichloro-4-(hydroxymethyl)benzoyl]-1H-pyrrolo[3,2-c]pyridin-4-yl}cyclopropanecarboxamide 
• 1415125-23-3 N-{1-[4-(bromomethyl)-2,6-dichlorobenzoyl]-1H-pyrrolo[3,2-c]pyridin-4-yl}cyclopropanecarboxamide 

Relevant articles and documents

PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION AND USE THEREOF

The present invention provides a phosphorus-containing compound characterized by being a compound represented by the following structure: the compound is a novel immune cell migration inhibitor. The compound has good hydrophilicity and can be developed into eye drops. The compound has a strong inhibitory ability to immune cell migration and can relieve the symptoms of most dry-eye patients.

HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A' B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.