264276-14-4

Basic information

• Product Name: dimethyl 2,6-dichlorobenzene-1,4-dioate
• Synonyms: dimethyl 2,6-dichlorobenzene-1,4-dioate;Dimethyl 2,6-dichloroterephthalate;2,6-Dichloro-terephthalic acid dimethyl ester;2,6-Dichloro-1,4-benzenedicarboxylic Acid Dimethyl Ester;Dimethyl 2,6-dichlorobenzene-1,4-dicarboxylate
• CAS NO: 264276-14-4
• Molecular Formula: C₁₀H₈Cl₂O₄
• Molecular Weight: 263.07412
• Mol File: 264276-14-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, DCM, Methanol
• CAS DataBase Reference: dimethyl 2,6-dichlorobenzene-1,4-dioate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2,6-dichlorobenzene-1,4-dioate(264276-14-4)
• EPA Substance Registry System: dimethyl 2,6-dichlorobenzene-1,4-dioate(264276-14-4)

Safety Data

• Hazardous Substances Data: 264276-14-4(Hazardous Substances Data)

Usage

Uses

2,6-Dichloro-1,4-benzenedicarboxylic Acid Dimethyl Ester is an intermediate in the synthesis of Zoxamide (Z700920), a fungacide for control of mildew and late bight.

Upstream product

• 116802-97-2 2,6-dichloroterephthalic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 1258298-04-2 2-amino-3,5-dichloro-4-(carbomethoxy)benzoic acid methyl ester 
• 5372-81-6 dimethyl aminoterephthalate 

Downstream Products

• 264272-64-2 2,6-dichlorobenzene-1,4-dicarboxylic acid,1-methyl ester 
• 1415124-87-6 methyl 2,6-dichloro-4-(methylcarbamoyl)benzoate 
• 1415125-37-9 2,6-dichloro-4-(methylcarbamoyl)benzoic acid 
• 1415124-95-6 methyl 2,6-dichloro-4-(hydroxymethyl)benzoate 
• 1415124-96-7 2,6-dichloro-4-(hydroxymethyl)benzoic acid 
• 1415123-49-7 3,5-dichloro-4-({7-[(cyclopropylcarbonyl)amino]-2-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl}carbonyl)-N-methylbenzamide 
• 1415125-25-5 2,6-dichloro-4-(methylcarbamoyl)benzoyl chloride 
• 1415124-56-9 3,5-dichloro-4-({3-chloro-4-[(cyclopropylcarbonyl)amino]-1H-pyrrolo[3,2-c]pyridin-1-yl}carbonyl)-N-methylbenzamide 
• 1415124-51-4 N-(1-{2,6-dichloro-4-[(methylamino)methyl]benzoyl}-1H-pyrrolo[3,2-c]pyridin-4-yl)cyclopropanecarboxamide 
• 1415125-23-3 N-{1-[4-(bromomethyl)-2,6-dichlorobenzoyl]-1H-pyrrolo[3,2-c]pyridin-4-yl}cyclopropanecarboxamide 
• 1415123-73-7 N-{1-[2,6-dichloro-4-(hydroxymethyl)benzoyl]-1H-pyrrolo[3,2-c]pyridin-4-yl}cyclopropanecarboxamide 
• 409127-32-8 methyl 2,6-dichloro-4-cyanobenzoate 
• 1258298-07-5 N-(2-bromopyridin-4-yl)-2,6-dichloro-4-cyanobenzamide 
• 1258298-06-4 2,6-dichloro-4-cyanobenzoyl chloride 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A′ B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.

HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A' B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.

New phenylalanine derivatives

Specific phenylalanine derivatives or pharmaceutically acceptable. salts thereof have an antagonistic effect on the α4 integrins and, therefore, are usable as therapeutic agents or preventive agents for diseases in which α4 integrin-depending adhesion process participates in the pathology, such as inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sj?gren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection.