141514-75-2

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 122136-03-2 ethyl 3-formyl-4-methoxybenzoate 
• 82304-99-2 3-formyl-4-hydroxybenzoic acid ethyl ester 
• 141514-74-1 ethyl α-azido-5-ethoxycarbonyl-2-methoxycinnamate 
• 603-35-0 triphenylphosphine 

Downstream Products

• 141514-82-1 1-(4-Chloro-phenyl)-5-methoxy-2-oxo-1,2-dihydro-pyrrolo[4,3,2-ij]isoquinoline-7-carboxylic acid ethyl ester 
• 141514-79-6 5-Methoxy-2-oxo-1-p-tolyl-1,2-dihydro-pyrrolo[4,3,2-ij]isoquinoline-7-carboxylic acid ethyl ester 
• 142212-30-4 1-(4-Fluoro-phenyl)-5-methoxy-2-oxo-1,2-dihydro-pyrrolo[4,3,2-ij]isoquinoline-7-carboxylic acid ethyl ester 
• 141514-81-0 5-Methoxy-1-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-pyrrolo[4,3,2-ij]isoquinoline-7-carboxylic acid ethyl ester 
• 141514-77-4 1-Benzyl-5-methoxy-2-oxo-1,2-dihydro-pyrrolo[4,3,2-ij]isoquinoline-7-carboxylic acid ethyl ester 
• 141514-78-5 5-Methoxy-2-oxo-1-phenyl-1,2-dihydro-pyrrolo[4,3,2-ij]isoquinoline-7-carboxylic acid ethyl ester 
• 141514-80-9 5-Methoxy-2-oxo-1-m-tolyl-1,2-dihydro-pyrrolo[4,3,2-ij]isoquinoline-7-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

An efficient one-pot synthesis of pyrrolo[4,3,2-ij]isoquinoline derivatives by a consecutive aza-wittig/electrocyclic ring-closure/intramolecular acylation process

Iminophosphorane, ethyl 5-ethoxycarbonyl-2-methoxy-α-[(triphenylphosphoranylidene)amino]cinn amate (4) reacts with aliphatic and aromatic isocyanates in toluene at 170°C to give directly the corresponding pyrrolo[4,3,2-ij]isoquinolines 8 in moderate yields.