1415214-16-2Relevant articles and documents
A new inorganic-organic hybrid material Al-SBA-15-TPI/H6P2W18O62 catalyzed one-pot, three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones
Tayebee,Amini,Pouyamanesh,Aliakbari
, p. 5888 - 5897 (2015)
A new inorganic-organic hybrid material Al-SBA-15-TPI/H6P2W18O62 was prepared and fully characterized by SEM, XRD, FT-IR, TGA-DTA, and UV-Vis spectroscopic techniques. Then, the prepared nanomaterial was used as a simple, cost-effective, and reusable heterogeneous catalyst for the synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives by a one-pot, three-component condensation reaction of phthalhydrazide, cyclic diones, and aromatic aldehydes under solvent free conditions at 100°C in a short time. This methodology has proven to be efficient and environmentally benign in terms of high yields and low reaction times and offers significant improvements with regard to the scope of transformation and simplicity of operation by avoiding expensive or corrosive catalysts.
Solvent-free, one-pot, four-component synthesis of 2H-indazolo[2,1-b] phthalazine-triones using sulfuric acid-modified PEG-6000 as a green recyclable and biodegradable polymeric catalyst
Hasaninejed, Alireza,Kazerooni, Maryam Rasekhi,Zare, Abdolkarim
, p. 148 - 155 (2013/01/15)
A green practical method for the efficient synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-triones using sulfuric acid-modified polyethylene glycol-6000 (PEG-OSO3H) as an eco-friendly polymeric catalyst from the four-component condensation reaction of phthalic anhydride, hydrazinium hydroxide, 1,3-cyclohexanedione or 5,5-dimethyl 1,3-cyclohexanedione (dimedone) and aromatic aldehydes under solvent-free conditions at 80 °C is described. This approach allowed the environmental impact factor (E-factor) to be minimized.
