1415218-22-2

Upstream product

• 1415218-21-1 p-tolyl 3-O-benzyl-4-O-p-methoxybenzyl-6-O-tert-butyl-diphenylsilyl-1-thio-α-L-idopyranoside 
• 123-76-2 levulinic acid 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 1415218-20-0 p-tolyl 2-O-benzoyl-3-O-benzyl-4-O-p-methoxybenzyl-6-O-tert-butyl-diphenylsilyl-1-thio-α-L-idopyranoside 
• 1242437-69-9 C₃₅H₃₆O₇S 

Relevant academic research and scientific papers

Obstacles and solutions for chemical synthesis of syndecan-3 (53–62) glycopeptides with two heparan sulfate chains

Proteoglycans play critical roles in many biological events. Due to their structural complexities, strategies towards synthesis of this class of glycopeptides bearing well-defined glycan chains are urgently needed. In this work, we give the full account o

Chemical synthesis of a heparan sulfate glycopeptide: Syndecan-1

Finishing first: The highly complex structure of the title compound (see picture) was assembled. The protective groups utilized, as well as the sequences for formation of the glycosyl linkages and protecting group removal are critical to the success of the synthesis. This first preparation of a heparan sulfate glycopeptide lays the foundation for accessing other members of this class of molecules. Copyright