1415219-01-0

Basic information

• Product Name: N-[(Z)-2-cyano-1-phenylethenyl]-N-ethyl-1-methyl-1H-imidazole-2-carboxamide
• Synonyms: N-[(Z)-2-cyano-1-phenylethenyl]-N-ethyl-1-methyl-1H-imidazole-2-carboxamide
• CAS NO: 1415219-01-0
• Molecular Weight: 280.329
• Mol File: 1415219-01-0.mol

Chemical Properties

• CAS DataBase Reference: N-[(Z)-2-cyano-1-phenylethenyl]-N-ethyl-1-methyl-1H-imidazole-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(Z)-2-cyano-1-phenylethenyl]-N-ethyl-1-methyl-1H-imidazole-2-carboxamide(1415219-01-0)
• EPA Substance Registry System: N-[(Z)-2-cyano-1-phenylethenyl]-N-ethyl-1-methyl-1H-imidazole-2-carboxamide(1415219-01-0)

Safety Data

• Hazardous Substances Data: 1415219-01-0(Hazardous Substances Data)

Upstream product

• 616-47-7 1-methyl-1H-imidazole 
• 935-02-4 3-Phenyl-2-propynonitrile 
• 109-90-0 ethyl isocyanate 

Relevant articles and documents

Three-component reaction between imidazoles, isocyanates, and cyanophenylacetylene: A short-cut to N-(Z)-alkenylimidazole-2-carboxamides

1-Substituted imidazoles, isocyanates, and cyanophenylacetylene react under mild (rt), non-catalytic solvent-free conditions to give (Z)-(2-cyano-1- phenylethenyl)imidazole-2-carboxamides in up to 72% yields and with ca. 100% stereoselectivity. The reaction starts from the initial formation of zwitterion/carbene intermediates captured by the isocyanate as the electrophile followed by migration of the alkenyl moiety from the N-3 atom to the anionic center at the carboxamide nitrogen. Thus, the reaction provides an easy access to a novel family of functionalized imidazoles.