1415346-05-2

Basic information

• Product Name: 4,6-dichloro-N-(6-fluoro-1-phenyl-1H-indol-5-yl)-N-(2-hydroxyethyl)pyrimidine-5-carboxamide
• Synonyms: 4,6-dichloro-N-(6-fluoro-1-phenyl-1H-indol-5-yl)-N-(2-hydroxyethyl)pyrimidine-5-carboxamide
• CAS NO: 1415346-05-2
• Molecular Weight: 445.28
• Mol File: 1415346-05-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,6-dichloro-N-(6-fluoro-1-phenyl-1H-indol-5-yl)-N-(2-hydroxyethyl)pyrimidine-5-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-dichloro-N-(6-fluoro-1-phenyl-1H-indol-5-yl)-N-(2-hydroxyethyl)pyrimidine-5-carboxamide(1415346-05-2)
• EPA Substance Registry System: 4,6-dichloro-N-(6-fluoro-1-phenyl-1H-indol-5-yl)-N-(2-hydroxyethyl)pyrimidine-5-carboxamide(1415346-05-2)

Safety Data

• Hazardous Substances Data: 1415346-05-2(Hazardous Substances Data)

Upstream product

• 1415346-04-1 N-(2-(tert-butyldimethylsilyloxy)ethyl)-4,6-dichloro-N-(6-fluoro-1-phenyl-1H-indol-5-yl)pyrimidine-5-carboxamide 
• 1415346-03-0 N-(2-(tert-butyldimethylsilyloxy)ethyl)-6-fluoro-1-phenyl-1H-indol-5-amine 
• 1415346-02-9 6-fluoro-1-phenyl-1H-indol-5-yl trifluoromethanesulfonate 
• 1415346-01-8 6-fluoro-1-phenyl-1H-indol-5-ol 
• 1415346-00-7 6-fluoro-5-methoxy-1-phenyl-1H-indole 
• 455-93-6 2-fluoro-1-methoxy-4-nitrobenzene 
• 63762-83-4 5-methoxy-6-fluoroindole 

Downstream Products

• 1415346-06-3 4-chloro-6-(6-fluoro-1-phenyl-1H-indol-5-yl)-7,8-dihydrooxazepino[2,3-d]pyrimidin-5(6H)-one 
• 1415345-12-8 4-amino-6-(6-fluoro-1-phenyl-1H-indol-5-yl)-7,8-dihydrooxazepino[2,3-d]pyrimidin-5(6H)-one 

Relevant articles and documents

NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS

This invention relates to novel compounds which are inhibitors of acyl coenzymeA: diacylglycerol acyltransferase 1 (DGAT-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the prevention or treatment of diseases related to DGAT-1 dysfunction or where modulation of DGAT-1 activity may have therapeutic benefit including but not limited to obesity, obesity related disorders, hypertriglyceridemia, hyperlipoproteinemia, chylomicronemia, dyslipidemia, non-alcoholic steatohepatitis, diabetes, insulin resistance, metabolic syndrome, hepatitis C virus infection and acne or other skin disorders.