1415351-65-3

Upstream product

• 15378-40-2 trans-1-cyclohexyl-2-buten-1-one 
• 79646-42-7 (2E,1R)-1-cyclohexyl-2-buten-1-ol 
• 88681-68-9 di(1H-imidazol-2-yl)methanethione 
• 18736-82-8 1-cyclohexyl-but-2-en-1-ol 
• 79646-42-7 (E)-1-cyclohexyl-2-buten-1-ol 

Downstream Products

• 1613417-00-7 (S)-(E)-S-4-cyclohexylbut-3-en-2-yl methyl(p-tolyl)carbamothioate 
• 1613417-02-9 (S)-(E)-S-4-cyclohexylbut-3-en-2-yl 4-fluorophenyl(methyl)carbamothioate 
• 1613417-03-0 (S)-(E)-S-4-cyclohexylbut-3-en-2-yl 4-chlorophenyl(methyl)carbamothioate 
• 1415351-95-9 (S)-(E)-S-4-cyclohexylbut-3-en-2-yl 3-methoxyphenyl(methyl)carbamothioate 
• 1613417-05-2 (S)-(E)-S-4-cyclohexylbut-3-en-2-yl 2-methoxyphenyl(methyl)carbamothioate 
• 1613417-08-5 (S)-(E)-S-4-cyclohexylbut-3-en-2-yl methyl(pyridin-2-yl)carbamothioate 
• 1613417-30-3 (S)-(E)-tert-butyl 6-(4-cyclohexyl-2-((methylcarbamoyl)thio)but-3-en-2-yl)-1H-indole-1-carboxylate 
• 1613416-91-3 (S)-(E)-4-cyclohexyl-2-(3-methoxyphenyl)but-3-ene-2-thiol 
• 1613416-97-9 (R)-(E)-tert-butyl 6-(4-cyclohexyl-2-mercaptobut-3-en-2-yl)-1H-indole-1-carboxylate 
• 1613417-10-9 (S)-(E)-tert-butyl 6-((((4-cyclohexylbut-3-en-2-yl)thio)carbonyl)(methyl)amino)-1H-indole-1-carboxylate 
• 1613417-22-3 (S)-(E)-S-4-cyclohexyl-2-(3-methoxyphenyl)but-3-en-2-yl methylcarbamothioate 
• 1613417-12-1 (S)-(E)-S-4-cyclohexylbut-3-en-2-yl 1H-indol-6-yl(methyl)carbamothioate 

Relevant academic research and scientific papers

Dihydrothiophenes containing quaternary stereogenic centres by sequential stereospecific rearrangements and ring-closing metathesis

Stereospecific [3,3]-sigmatropic rearrangement of O-substituted thiocarbamate derivatives of enantiopure allylic alcohols provides allylic thiocarbamates as single enantiomers. Intramolecular arylation by rearrangement of their allyllithium derivatives provides allylic tertiary thiols. Allylation and ring-closing metathesis gives 2,5-dihydrothiophenes containing sulfur-bearing quaternary centres. This journal is the Partner Organisations 2014.

S-allyl thiocarbamates from allylic alcohols by in situ [3,3]-sigmatropic rearrangement of a thiocarbonyldiimidazole adduct

Treatment of allylic alcohols with thiocarbonyldiimidazole generates an unstable O-allyl imidazolyl thione ester, which rearranges spontaneously and in high yield to the corresponding S-allyl imidazolyl thiol ester. Displacement of the imidazole by N-alky