1415419-78-1

Basic information

• Product Name: 2-[2-(4-chlorobenzoyl)-5-methoxyphenyl]benzoxazole
• Synonyms: 2-[2-(4-chlorobenzoyl)-5-methoxyphenyl]benzoxazole
• CAS NO: 1415419-78-1
• Molecular Weight: 363.8
• Mol File: 1415419-78-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[2-(4-chlorobenzoyl)-5-methoxyphenyl]benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(4-chlorobenzoyl)-5-methoxyphenyl]benzoxazole(1415419-78-1)
• EPA Substance Registry System: 2-[2-(4-chlorobenzoyl)-5-methoxyphenyl]benzoxazole(1415419-78-1)

Safety Data

• Hazardous Substances Data: 1415419-78-1(Hazardous Substances Data)

Upstream product

• 32959-59-4 2-(3-methoxyphenyl)benzoxazole 
• 104-88-1 4-chlorobenzaldehyde 

Relevant articles and documents

Palladium-catalyzed ortho-acylation of 2-arylbenzoxazoles

An efficient and facile catalytic protocol for benzoxazole-directed ortho-acylation of 2-arylbenzoxazoles has been described using aldehydes as the easily accessible acyl source. This catalytic system was performed in the presence of tert-butyl hydroperoxide (TBHP) as the oxidant in chlorobenzene, affording the acylated 2-arylbenzoxazoles in moderate to good yields. The acylation exhibited high regioselectivity for the substrates containing a meta-substituent in the benzene ring and typically occurred at the less sterically hindered ortho-C-H bond of the directing group.