1415476-02-6Relevant articles and documents
Diastereoselective synthesis of CF3-substituted, epoxide-fused heterocycles with β-(trifluoromethyl)vinylsulfonium salts
Fritz, Sven P.,West, Thomas H.,McGarrigle, Eoghan M.,Aggarwal, Varinder K.
, p. 6370 - 6373 (2012)
CF3-substituted vinyl diphenylsulfonium triflate is an effective annulation reagent for the formation of α-CF3 substituted, epoxide-fused heterocycles (pyrrolidines, piperidines, and tetrahydrofurans). This simple method affords a variety of valuable heterocyclic building blocks in a highly diastereoselective manner (dr >20:1).