141550-22-3

Upstream product

• 141566-51-0 (5R,7S,2E)-5-hydroxy-7,8-dimethoxy-4,4-dimethyl-2-octene 
• 141550-19-8 (1Z,4R,6R,8S)-6-benzyloxy-1-chloro-4-hydroxy-8,9-dimethoxy-5,5-dimethyl-1-nonene 
• 141550-23-4 (2E,5R,7S)-5-benzyloxy-7,8-dimethoxy-4,4-dimethyl-2-octene 
• 73787-19-6 (3R,5S)-3-benzyloxy-5,6-dimethoxy-2,2-dimethyl-hexanal 
• 98-88-4 benzoyl chloride 
• 85708-43-6 (4R,6R,8S)-4,6-dihydroxy-8,9-dimethoxy-5,5-dimethyl-1-nonene 

Relevant academic research and scientific papers

Allylboration-reactions, the key to a short synthesis of benzoyl-pedamide

Benzoyl-pedamide (2) a key building block for the synthesis of pederin, has been synthesized in 13 steps from malic acid. The new stereogenic centers have been generated under reagent control of diastereoselectivity with selectivities of 87 and 80% using the newly developed chiral α-substituted allylboronate 16 as well as 21 as reagents.