1415501-64-2

Upstream product

• 1663-39-4 tert-Butyl acrylate 
• 727985-37-7 ?(2-bromo-5-methylphenyl)methanol 

Downstream Products

• 1415501-65-3 tert-butyl (2E)-3-[2-(bromomethyl)-4-methylphenyl]acrylate 
• 1415501-67-5 methyl (S,2R)-1-{benzyl[(1R)-1-phenylethyl]amino}-5-methylindane-2-carboxylate 
• 1415501-66-4 tert-butyl (1S,2R)-1-{benzyl[(1R)-1-phenylethyl]amino}-5-methylindane-2-carboxylate 

Relevant academic research and scientific papers

IMIDAZOPYRIDINE COMPOUNDS

[Problem] An excellent drug for treating or preventing cardiovascular diseases, based on cGMP production enhancing action due to soluble guanylate cyclase activating action, is provided. [Means for Solution] It was found that imidazopyridine compounds having a carbamoyl group at the 3-position and a substituent bonded at the 8-position via an oxygen atom in an imidazo[1,2-a]pyridine skeleton exhibits a cGMP production enhancing action by a potent soluble guanylate cyclase activating action, and is useful as a drug for treating or preventing various soluble guanylate cyclase-related cardiovascular diseases, thereby completing the present invention.