727985-37-7

Basic information

• Product Name: (2-bromo-5-methylphenyl)methanol
• Synonyms: (2-bromo-5-methylphenyl)methanol;2-bromo-5-methylbenzenemethanol
• CAS NO: 727985-37-7
• Molecular Formula: C₈H₉BrO
• Molecular Weight: 201.06046
• Mol File: 727985-37-7.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-bromo-5-methylphenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-5-methylphenyl)methanol(727985-37-7)
• EPA Substance Registry System: (2-bromo-5-methylphenyl)methanol(727985-37-7)

Safety Data

• Hazardous Substances Data: 727985-37-7(Hazardous Substances Data)

Usage

Description

(2-bromo-5-methylphenyl)methanol is a chemical compound with the molecular formula C8H9BrO. It is a white to off-white solid that is soluble in organic solvents.

Uses

Used in Organic Synthesis:
(2-bromo-5-methylphenyl)methanol is used as a reagent for the preparation of various pharmaceutical, agrochemical, and material science compounds.
Used in Pharmaceutical Industry:
(2-bromo-5-methylphenyl)methanol is used as a starting material for the synthesis of new drugs.
Used in Agrochemical Industry:
(2-bromo-5-methylphenyl)methanol is used as a precursor for the development of new agrochemicals.
Used in Material Science:
(2-bromo-5-methylphenyl)methanol is used as a building block for the creation of new materials.
Used in Antimicrobial Agents Development:
(2-bromo-5-methylphenyl)methanol is used as an active ingredient for the development of new antimicrobial agents due to its antibacterial and antifungal properties.
Used in Medicine and Biochemistry:
(2-bromo-5-methylphenyl)methanol is used as an enzyme inhibitor, suggesting potential applications in the fields of medicine and biochemistry.

Upstream product

• 6967-82-4 2-bromo-5-methylbenzoic acid 
• 90221-55-9 2-bromo-5-methylbenzaldehyde 
• 90971-88-3 methyl 2-bromo-5-methylbenzoate 
• 2941-78-8 2-Amino-5-methylbenzoic acid 

Downstream Products

• 905710-68-1 4-bromo-3-(methoxymethoxymethyl)toluene 
• 1415501-64-2 tert-butyl (2E)-3-[2-(hydroxymethyl)-4-methylphenyl]acrylate 
• 1415501-67-5 methyl (S,2R)-1-{benzyl[(1R)-1-phenylethyl]amino}-5-methylindane-2-carboxylate 
• 1415501-66-4 tert-butyl (1S,2R)-1-{benzyl[(1R)-1-phenylethyl]amino}-5-methylindane-2-carboxylate 
• 1415501-65-3 tert-butyl (2E)-3-[2-(bromomethyl)-4-methylphenyl]acrylate 
• 1420532-44-0 1-(2-bromo-5-methylbenzyl)-5-methyl-1H-1,2,3-triazole 
• 1420532-43-9 1-(2-bromo-5-methylbenzyl)-5-methyl-4-(trimethylsilyl)-1H-1,2,3-triazole 
• 1420532-42-8 2-(azidomethyl)-1-bromo-4-methyl benzene 
• 27561-50-8 1-bromo-2-(bromomethyl)-4-methylbenzene 
• 90221-55-9 2-bromo-5-methylbenzaldehyde 
• 1261751-19-2 ethyl 3-(2-bromo-5-methylphenyl)propanoate 

Relevant articles and documents

Bimetal Cooperatively Catalyzed Arylalkynylation of Alkynylsilanes

An unprecedented Pd/Rh cooperatively catalyzed arylalkynylation of alkynylsilanes was developed to merge an alkynylidene moiety with benzosilacycle. These silaarenes possess a particular aggregation-induced emission behavior. Mechanistic investigations demonstrate that the relay trimetallic transmetalation plays a pivotal role in governing this transformation.

Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist

The long chain free fatty acid receptor 4 (FFA4/GPR120) has recently been recognized as lipid sensor playing important roles in nutrient sensing and inflammation and thus holds potential as a therapeutic target for type 2 diabetes and metabolic syndrome. To explore the effects of stimulating this receptor in animal models of metabolic disease, we initiated work to identify agonists with appropriate pharmacokinetic properties to support progression into in vivo studies. Extensive SAR studies of a series of phenylpropanoic acids led to the identification of compound 29, a FFA4 agonist which lowers plasma glucose in two preclinical models of type 2 diabetes.

Formation of Benzo[ b ]Thiophenes by Electroreduction of Tert-Alkanecarbodithioates

The electroreduction of a 1:1-mixture of 2-bromobenzyl 2,2-dimethylpropanedithioate and 2-bromo-5-methylbenzyl 2,2-dimethylbutanedithioate led to a mixture of 2-Tert-butylbenzo[b]thiophene, 2-Tert-Amylbenzo[b]thiophene, 2-Tert-butyl-5-methylbenzo[b]thioph