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• 824-79-3 sodium 4-methylbenzenesulfinate 
• 139446-55-2 3-(2-thienyl)-3-butenoic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 30616-73-0 2-isopropenylthiophene 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Relevant academic research and scientific papers

Allylic C-S Bond Construction through Metal-Free Direct Nitroalkene Sulfonation

A metal-free, open-flask protocol was developed for the preparation of allylic sulfones through direct condensation of sodium arylsulfinates and β,β-disubstituted nitroalkenes. The key step of this process was the Lewis base-promoted equilibrium between nitroalkenes and allylic nitro compounds. Through this process, the readily available conjugated nitroalkenes can be easily converted into allylic nitro compounds, which contain more reactive C=C bonds toward the sulfonyl radical addition. As a result, allylic sulfones were prepared in excellent yields with a broad substrate scope under mild conditions.

Process for the selective synthesis of allyl sulfone compounds

The invention relates to a method for selectively synthesizing an allylic sulfone compound. The method comprises the steps of: adding solvent to raw materials of nitroolefin and sodium sulfinate whichis stable and easy to operate, directly heating the obtained mixture while stirring is conduced, and performing treatment on the heated mixture to obtain the allylic sulfone compound. The method hasthe advantages that no addition of catalysts is needed, the whole system is open, and the yield is high; through the adoption of the direct heating method, the sodium sulfinate can be used as a mild Lewis base in the above reaction; the key step of the reaction is that the equilibrium between the nitroolefin and an allyl nitro compound is promoted by the Lewis base, and the stable nitroolefin is converted into the allyl nitro compound, which is more prone to a free-radical addition reaction, through the key step; therefore, the reaction can be conducted more easily under a mild condition, andthe speed of the reaction is increased, so that the compound with an allylic sulfone structure is effectively synthesized.

Copper-Catalyzed Decarboxylative Functionalization of Conjugated β, Γ-Unsaturated Carboxylic Acids

Copper-catalyzed decarboxylative coupling reactions of conjugated β,γ-unsaturated carboxylic acids have been achieved for allylic amination, alkylation, sulfonylation, and phosphinoylation. This approach was effective for a broad scope of amino, alkyl, su

Iodine-Catalyzed Facile Approach to Sulfones Employing TosMIC as a Sulfonylating Agent

A novel iodine-catalyzed functionalization of a variety of olefins and alkynes and direct decarboxylative functionalization of cinnamic and propiolic acids with TosMIC to provide access to various vinyl, allyl, and β-iodo vinylsulfones is described. This simple, efficient, and environmentally benign approach employing inexpensive molecular iodine as a catalyst demonstrates a versatile protocol for the synthesis of highly valuable sulfones, rendering it attractive to both synthetic and medicinal chemistry.

Tetrabutylammonium iodide catalyzed allylic sulfonylation of α-methyl styrene derivatives with sulfonylhydrazides

Sulfonyl radicals generated from sulfonylhydrazides by the Bu 4NI-tert-butyl hydroperoxide (TBHP) catalysis system underwent addition to a variety of α-methyl styrene derivatives to give the corresponding allylic sulfones. This selective allylic sulfonylation is metal-free, operationally simple, and environmentally friendly. The Royal Society of Chemistry 2012..