1415666-25-9Relevant articles and documents
Intercepting the Breslow intermediate via Claisen rearrangement: Synthesis of complex tertiary alcohols without organometallic reagents
Alwarsh, Sefat,Ayinuola, Kolawole,Dormi, Silvana S.,McIntosh, Matthias C.
supporting information, p. 3 - 5 (2013/03/28)
A novel Claisen rearrangement in which the Breslow intermediate is engaged as a hydroxy-substituted N,S-ketene acetal to provide complex 3° alcohols without the use of organometallic reagents is reported. The reaction constitutes an unprecedented reactivi