1415743-33-7

Basic information

• Product Name: 3-[7-methoxy-6-(4-nitrophenylazo)-3,4-dihydro-2H-quinolin-1-yl]propane-1-sulfonic acid 2,2,2-trifluoro-1-p-tolyl-ethyl ester
• Synonyms: 3-[7-methoxy-6-(4-nitrophenylazo)-3,4-dihydro-2H-quinolin-1-yl]propane-1-sulfonic acid 2,2,2-trifluoro-1-p-tolyl-ethyl ester
• CAS NO: 1415743-33-7
• Molecular Weight: 606.623
• Mol File: 1415743-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[7-methoxy-6-(4-nitrophenylazo)-3,4-dihydro-2H-quinolin-1-yl]propane-1-sulfonic acid 2,2,2-trifluoro-1-p-tolyl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[7-methoxy-6-(4-nitrophenylazo)-3,4-dihydro-2H-quinolin-1-yl]propane-1-sulfonic acid 2,2,2-trifluoro-1-p-tolyl-ethyl ester(1415743-33-7)
• EPA Substance Registry System: 3-[7-methoxy-6-(4-nitrophenylazo)-3,4-dihydro-2H-quinolin-1-yl]propane-1-sulfonic acid 2,2,2-trifluoro-1-p-tolyl-ethyl ester(1415743-33-7)

Safety Data

• Hazardous Substances Data: 1415743-33-7(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 446-65-1 2,2,2-trifluoro-1-(4-methylphenyl)ethanol 
• 1415743-31-5 3-(7-methoxy-3,4-dihydro-2H-quinolin-1-yl)propane-1-sulfonic acid 2,2,2-trifluoro-1-p-tolyl-ethyl ester 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 1415743-29-1 3-iodopropane-1-sulfonic acid 2,2,2-trifluoro-1-p-tolyl-ethyl ester 
• 1415743-28-0 3-chloropropane-1-sulfonic acid 2,2,2-trifluoro-1-p-tolyl-ethyl ester 

Relevant articles and documents

A trifluoroacetic acid-labile sulfonate protecting group and its use in the synthesis of a near-IR fluorophore

Sulfonated molecules exhibit high water solubility, a property that is valuable for many biological applications but often complicates their synthesis and purification. Here we report a sulfonate protecting group that is resistant to nucleophilic attack but readily removed with trifluoroacetic acid (TFA). The use of this protecting group improved the synthesis of a sulfonated near-IR fluorophore and the mild deprotection conditions allowed isolation of the product without requiring chromatography.