1415797-75-9

Upstream product

• 1415797-74-8 methyl 4-(4-fluorophenyl)-5-oxo-4,5-dihydrothiazolo[5,4-b]pyridine-6-formate 
• 1378728-45-0 ethyl 5-(4-fluorophenylamino)thiazole-4-formate 
• 1544-68-9 4-fluorophenyl isothiocyanate 
• 371-40-4 4-fluoroaniline 
• 1415797-73-7 C₁₅H₈F₄N₂O₆S₂ 
• 1415797-71-5 4-(4-fluorophenyl)-6-(methoxycarbonyl)-5-oxo-4,5-dihydrothiazolo[5,4-b]pyridine-7-oxy sodium salt 
• 1415797-72-6 ethyl 5-(N-(4-fluorophenyl)-2-methoxycarbonylacetamido)thiazole-4-formate 

Downstream Products

• 1415798-17-2 N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thiophene[3,2-b]pyridine-7-oxy)phenyl)-4-(4-fluorophenyl)-5-oxo-4,5-dihydrothiazolo[5,4-b]pyridine-6-formamide 
• 1415798-19-4 C₂₆H₁₆F₂N₆O₃S 
• 1415798-20-7 N-(3-fluoro-4-(2-(tetrahydropyrrole-1-formamide)pyridine-4-oxy)phenyl)-4-(4-fluoro phenyl)-5-oxo-4,5-dihydrothiazolo[5,4-b]pyridine-6-formamide 
• 1415798-12-7 N-(4-(2-aminopyridine-4-oxy)-3-fluorophenyl)-4-(4-fluorophenyl)-5-oxo-4,5-dihydrothiazolo[5,4-b]pyridine-6-formamide 
• 1415798-14-9 N-(3-fluoro-4-(7-methoxyquinoline-4-oxy)phenyl)-4-(4-fluorophenyl)-5-oxo-4,5-dihydrothiazolo[5,4-b]pyridine-6-formamide 
• 1415797-78-2 C₃₄H₂₄F₂N₆O₄S 

Relevant academic research and scientific papers

HETEROCYCLIC PYRIDONE COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF

The present invention relates to a heterocyclic pyridone compound represented by General Formula (I), where the heterocyclic pyridone compound is used as a tyrosine kinase inhibitor, and particularly a c-Met inhibitor. The present invention also relates to intermediates for preparing heterocyclic pyridone compound and a preparation method. The present invention further relates to a pharmaceutical composition containing the heterocyclic pyridone compound as an active ingredient, and a use of the pharmaceutical composition in treatment of diseases associated with tyrosine kinase c-Met, especially cancer associated with c-Met, as a medicament.