1415797-76-0

Basic information

• Product Name: 3-chloro-4-(2-fluoro-4-nitrophenyloxy)pyridine-2-amine
• Synonyms: 3-chloro-4-(2-fluoro-4-nitrophenyloxy)pyridine-2-amine
• CAS NO: 1415797-76-0
• Molecular Weight: 283.646
• Mol File: 1415797-76-0.mol

Chemical Properties

• CAS DataBase Reference: 3-chloro-4-(2-fluoro-4-nitrophenyloxy)pyridine-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-4-(2-fluoro-4-nitrophenyloxy)pyridine-2-amine(1415797-76-0)
• EPA Substance Registry System: 3-chloro-4-(2-fluoro-4-nitrophenyloxy)pyridine-2-amine(1415797-76-0)

Safety Data

• Hazardous Substances Data: 1415797-76-0(Hazardous Substances Data)

Upstream product

• 403-19-0 2-fluoro-4-nitrophenol 
• 1203499-43-7 tert-butyl (3,4-dichloropyridin-2-yl)carbamate 
• 959578-03-1 3,4-dichloropyridine-2-carboxylic acid 
• 55934-00-4 3,4-dichloropyridine 
• 188577-69-7 2-amino-3,4-dichloropyridine 

Downstream Products

• 1415798-46-7 C₂₅H₁₇ClF₂N₆O₃ 
• 1025720-94-8 BMS-777607 
• 1415798-51-4 N-(4-(2-amino-3-chloropyridine-4-oxy)-3-fluorophenyl)-5-(4-fluorophenyl)-4-methyl-6-oxo-3,4,5,6-tetrahydro-2H-pyrido[3,2-b][1,4]oxazine-7-formamide 
• 1415798-36-5 N-(4-(2-amino-3-chloropyridine-4-oxy)-3-fluorophenyl)-2-(dimethylamino)-4-(4-fluorophenyl)-5-oxo-4,5-dihydro-thiazolo[5,4-b]pyridine-6-formamide 
• 1415798-13-8 N-(4-(2-amino-3-chloropyridine-4-oxy)-3-fluorophenyl)-4-(4-fluorophenyl)-5-oxo-4,5-dihydrothiazolo[5,4-b]pyridine-6-formamide 

Relevant articles and documents

PHOSPHONATE CONJUGATES AND USES THEREOF

Phosphonate conjugates, preferably, bisphosphonate conjugates; methods of inhibiting Ron receptor tyrosine kinase and methods of treatment of bone destruction due to cancer or other conditions utilizing the provided phosphonate conjugates.

HETEROCYCLIC PYRIDONE COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF

The present invention relates to a heterocyclic pyridone compound represented by General Formula (I), where the heterocyclic pyridone compound is used as a tyrosine kinase inhibitor, and particularly a c-Met inhibitor. The present invention also relates to intermediates for preparing heterocyclic pyridone compound and a preparation method. The present invention further relates to a pharmaceutical composition containing the heterocyclic pyridone compound as an active ingredient, and a use of the pharmaceutical composition in treatment of diseases associated with tyrosine kinase c-Met, especially cancer associated with c-Met, as a medicament.