188577-69-7

Basic information

• Product Name: 2-AMINO-3,4-DICHLOROPYRIDINE
• Synonyms: 2-AMINO-3,4-DICHLOROPYRIDINE;2-Pyridinamine,3,4-dichloro-(9CI);3,4-dichloropyridin-2-amine;3,4-Dichloro-2-pyridinaMine;3,4-Dichloro-pyridin-2-ylamine
• CAS NO: 188577-69-7
• Molecular Formula: C5H4Cl2N2
• Molecular Weight: 163
• Product Categories: HALIDE;API intermediates;Pyridines
• Mol File: 188577-69-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 93-95℃
• Boiling Point: 245℃
• Flash Point: 102℃
• Appearance: /
• Density: 1.497
• Vapor Pressure: 0.029mmHg at 25°C
• Refractive Index: 1.623
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 2-AMINO-3,4-DICHLOROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-3,4-DICHLOROPYRIDINE(188577-69-7)
• EPA Substance Registry System: 2-AMINO-3,4-DICHLOROPYRIDINE(188577-69-7)

Safety Data

• Hazardous Substances Data: 188577-69-7(Hazardous Substances Data)

Usage

Description

2-Amino-3,4-Dichloropyridine, with the CAS number 72226-42-3, is an aromatic halogen and a member of the pyridine family. It is a heterocyclic aromatic compound that features a six-membered ring with one nitrogen atom and five carbon atoms. 2-AMINO-3,4-DICHLOROPYRIDINE is distinguished by the presence of an amino group (-NH2) and two chlorine atoms attached to the pyridine ring. It is utilized in various applications within scientific research, particularly in the synthesis of pharmaceutical products. Before use, it is essential to consult a Material Safety Data Sheet (MSDS) for its physical and chemical properties, safety, toxicity, and handling information.

Uses

Used in Pharmaceutical Synthesis:
2-Amino-3,4-Dichloropyridine is used as a key intermediate in the synthesis of pharmaceutical products. Its unique structure allows for the creation of various drug molecules, contributing to the development of new medications.
Used in Scientific Research:
In the field of scientific research, 2-Amino-3,4-Dichloropyridine is employed as a reagent or building block for the synthesis of complex organic compounds. Its versatility in chemical reactions makes it a valuable tool for researchers working on the development of new chemical entities and materials.

InChI:InChI=1/C5H4Cl2N2/c6-3-1-2-9-5(8)4(3)7/h1-2H,(H2,8,9)

Upstream product

• 55934-02-6 2,3,4-trichloropyridine 
• 96245-97-5 3-bromo-2,4-dihydroxypyridine 
• 103792-81-0 3-chloro-pyridine-2,4-diol 
• 626-03-9 3-deazauracil 
• 19798-80-2 2-Amino-4-chloropyridine 

Downstream Products

• 1415797-76-0 3-chloro-4-(2-fluoro-4-nitrophenyloxy)pyridine-2-amine 
• 1415798-46-7 C₂₅H₁₇ClF₂N₆O₃ 
• 1415798-51-4 N-(4-(2-amino-3-chloropyridine-4-oxy)-3-fluorophenyl)-5-(4-fluorophenyl)-4-methyl-6-oxo-3,4,5,6-tetrahydro-2H-pyrido[3,2-b][1,4]oxazine-7-formamide 
• 1415798-36-5 N-(4-(2-amino-3-chloropyridine-4-oxy)-3-fluorophenyl)-2-(dimethylamino)-4-(4-fluorophenyl)-5-oxo-4,5-dihydro-thiazolo[5,4-b]pyridine-6-formamide 
• 856965-68-9 3,4-dichloropyridin-2(1H)-one 

Relevant articles and documents

An improved large scale synthesis of 2-amino-4-chloropyridine and its use for the convenient preparation of various polychlorinated 2-aminopyridines

An efficient large scale synthesis of 2-amino-4-chloropyridine (3) has been achieved through a modification of existing literature procedures. Compound 3 was used to prepare the previously unreported 2-amino-4,5-dichloropyridine (4). The known 2-amino-3,4-dichloropyridine (5) and 2-amino-3,4,5-trichloropyridine (6) were pepared from 3 by new routes and in higher yields than previously reported.