141593-49-9Relevant academic research and scientific papers
PESTICIDAL SUBSTITUTED 1,2,5,-THIADIAZOLE DERIVATIVES
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Page/Page column 37-38, (2008/06/13)
Insecticidal and acaricidal compositions comprising an insecticidally or acaricidally effective amount of a 1,2,5-thiadiazole of the formula (I); wherein R, Q and m are as defined in admixture with at least one agriculturally acceptable extender or adjuvant are disclosed. In addition, methods of controlling insects and acarids comprising applying said compositions to a locus of crops where control is desired are disclosed.
Muscarinic analgesics with potent and selective effects on the gastrointestinal tract: Potential application for the treatment of irritable bowel syndrome
Mitch, Charles H.,Brown, Thomas J.,Bymaster, Frank P.,Calligaro, David O.,Dieckman, Donna,Merrit, Leander,Peters, Steven C.,Quimby, Steven J.,Shannon, Harlan E.,Shipley, Lisa A.,Ward, John S.,Hansen, Kristian,Olesen, Preben H.,Sauerberg, Per,Sheardown, Malcolm J.,Swedberg, Michael D. B.,Suzdak, Peter,Greenwood, Beverley
, p. 538 - 546 (2007/10/03)
Irritable bowel syndrome (IBS) is a pathophysiolocal condition characterized by abnormal bowel habits that are frequently accompanied by abdominal pain. Current therapy based on reducing high-amplitude GI contractions with nonselective muscarinic antagoni
Central cholinergic agents. III. Synthesis of 2-alkoxy-2,8-diazaspiro[4.5]decane-1,3-diones as muscarinic agonists
Ishihara,Yukimasa,Miyamoto,Goto
, p. 1177 - 1185 (2007/10/02)
A series of 2-alkoxy-2,8-diazaspiro[4.5]decane-1,3-diones and related compounds were synthesized and tested for muscarinic receptor binding affinity using [3H]pirenzepine and [3H]oxotremorine M as ligands. They were also evaluated fo
