1415964-26-9Relevant academic research and scientific papers
Perfluorinated Bis(dihydrooxazole) complexes immobilized on fluorous reversed-phase silica gel as recyclable catalysts for enantioselective dielsi-alder reactions
Hensle, Eva M.,Bannwarth, Willi
, p. 2072 - 2083 (2013/02/23)
The three different perfluoroalkyl-tagged bis(dihydrooxazole)copper complexes 19-21 were synthesized and immobilized noncovalently on fluorous reversed-phase silica gel (FRPSG) by fluorous-fluorous interactions (Schemes2 and 3). These supported catalysts were successfully applied to asymmetric Diels-Alder reactions in H2O and in CH2Cl2 (Schemea 4). Besides high conversion of the dienophile, we observed enantiomer excesses of up to 88% in H2O and 97% in CH2Cl2, and we were able to recover and re-use these catalytic systems several times. Despite the relatively high catalyst loading, the leaching of copper was remarkably low ranging from 2.4 to 5.9 ppm.
