1415980-85-6

Basic information

• Product Name: C₁₆H₁₇BrN₄
• Synonyms: C₁₆H₁₇BrN₄
• CAS NO: 1415980-85-6
• Molecular Weight: 345.242
• Mol File: 1415980-85-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₇BrN₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₇BrN₄(1415980-85-6)
• EPA Substance Registry System: C₁₆H₁₇BrN₄(1415980-85-6)

Safety Data

• Hazardous Substances Data: 1415980-85-6(Hazardous Substances Data)

Upstream product

• 5049-61-6 2-Aminopyrazine 
• 119072-55-8 tert-butylisonitrile 
• 873-75-6 4-bromobenzenemethanol 
• 1122-91-4 4-bromo-benzaldehyde 
• 163133-86-6 pyrimidin-4-amine 

Downstream Products

• 1415132-89-6 2-(4-bromophenyl)imidazo[1,2-a]pyrazin-3-amine 
• 1620074-80-7 C₂₁H₁₇BrN₄O₂ 

Relevant articles and documents

INHIBITORS OF TRANSCRIPTION FACTORS AND USES THEREOF

The present invention provides novel compounds of any one of Formulae (I) to (IV), and pharmaceutically compositions thereof. Compounds of any one of Formulae (I) to (IV) are believed to be inhibitors of bromodomain-containing proteins (e.g., bromo and ex

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provided.

Tandem approach for the synthesis of imidazo[1,2-a]pyridines from alcohols

Propylphosphonic anhydride (T3P) is shown to be an effective and mild reagent for the one-pot synthesis of imidazo[1,2-a]pyridines from a variety of alcohols. Alcohols are oxidized in situ to aldehydes under mild conditions, which in turn undergo a three-component reaction with various 2-aminopyridines and isocyanides to afford imidazo[1,2-a]pyridines in excellent yields. T3P acts as an activator for both DMSO in oxidation reaction and the Schiff base in nucleophilic addition reaction with isocyanides.