1416000-85-5

Basic information

• Product Name: tert-butyl 3-(9-oxo-10-(3-(trifluoromethyl)phenyl)-9,10-dihydropyrido[3,2-c][1,5]naphthyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-1-carboxylate
• Synonyms: tert-butyl 3-(9-oxo-10-(3-(trifluoromethyl)phenyl)-9,10-dihydropyrido[3,2-c][1,5]naphthyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-1-carboxylate
• CAS NO: 1416000-85-5
• Molecular Weight: 557.532
• Mol File: 1416000-85-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(9-oxo-10-(3-(trifluoromethyl)phenyl)-9,10-dihydropyrido[3,2-c][1,5]naphthyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(9-oxo-10-(3-(trifluoromethyl)phenyl)-9,10-dihydropyrido[3,2-c][1,5]naphthyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-1-carboxylate(1416000-85-5)
• EPA Substance Registry System: tert-butyl 3-(9-oxo-10-(3-(trifluoromethyl)phenyl)-9,10-dihydropyrido[3,2-c][1,5]naphthyridin-2-yl)-1H-pyrrolo[2,3-b]pyridin-1-carboxylate(1416000-85-5)

Safety Data

• Hazardous Substances Data: 1416000-85-5(Hazardous Substances Data)

Upstream product

• 127094-57-9 4,6-dichloro-(1,5)-naphthyridine-3-carboxylic acid ethyl ester 
• 1416000-52-6 ethyl 6-chloro-4-((3-(trifluoromethyl)phenyl)amino)-1,5-naphthyridine-3-carboxylate 
• 1416000-54-8 6-chloro-4-((3-(trifluoromethyl)phenyl)amino)-1,5-naphthyridine-3-carbaldehyde 
• 942070-47-5 2-methyl-2-propanyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate 
• 1416000-57-1 2-chloro-10-(3-(trifluoromethyl)phenyl)pyrido[3,2-c][1,5]naphthyridin-9(10H)-one 
• 1438413-72-9 C₁₆H₁₁ClF₃N₃O 
• 4487-59-6 2-bromo-5-nitropyridine 
• 13534-97-9 6-bromopyridine-3-amine 
• 1220700-73-1 diethyl 2-(((6-bromopyridin-3-yl)amino)methylene)malonate 
• 1184919-05-8 ethyl 6-bromo-4-hydroxy-1,5-naphthyridine-3-carboxylate 

Downstream Products

• 1415999-96-0 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-10-(3-(trifluoromethyl)phenyl)pyrido[3,2-c][1,5] naphthyridin-9(10H)-one 

Relevant articles and documents

Pyridonaphthyridine PI3K/MTOR Dual Inhibitors and Preparation and Use Thereof

The present invention relates to a pyridonaphthyridine compound as represented by general formula (I), which has a dual PI3K and mTOR inhibition effect, and its pharmaceutically acceptable salt, stereoisomer and deuteride thereof, wherein R1, R2, R3, R4, R5, R6, R7 and X are as defined in the specification; the present invention also relates to a method for preparing said compound, a pharmaceutical composition and a pharmaceutical formulation containing said compound, and uses of said compound in treating and/or preventing a proliferative disease and in the manufacture of a medicament for treating and/or preventing a proliferative disease.