1416007-23-2Relevant academic research and scientific papers
An efficient synthesis of (7S,10R)-2-bromo-5,6,7,8,9,10-hexahydro-7,10- epiminocyclohepta[b]indole: Application in the preparation and structural confirmation of a potent 5-HT6 antagonist
Isherwood, Matthew L.,Guzzo, Peter R.,Henderson, Alan J.,Hsia, Ming Min,Kaur, Jagjit,Nacro, Kassoum,Narreddula, Venkateswara R.,Panduga, Shailaja,Pathak, Rashmi,Shimpukade, Bharat,Tan, Valentina,Xiang, Kai,Qiang, Zhu,Ghosh, Animesh
, p. 1522 - 1527 (2013/02/23)
(7S,10R)-5-Methyl-2-((3-(trifluoromethyl)phenyl)sulfonyl)-5,6,7,8,9, 10-hexahydro-7,10-epiminocyclohepta[b]indole 1a is a potent 5-HT6 antagonist (h5-HT6 Ki = 1.5 nM) which is derived from an epiminocyclohept[b]indole scaf
