1416254-97-1

Basic information

• Product Name: C₂₇H₃₇NO₂
• CAS NO: 1416254-97-1
• Molecular Weight: 407.596
• Mol File: 1416254-97-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₇NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₇NO₂(1416254-97-1)
• EPA Substance Registry System: C₂₇H₃₇NO₂(1416254-97-1)

Safety Data

• Hazardous Substances Data: 1416254-97-1(Hazardous Substances Data)

Upstream product

• 1416255-02-1 C₂₈H₃₇NO₂ 
• 116233-17-1 3-methyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylamine 

Relevant articles and documents

Structure-activity relationship study on benzoic acid part of diphenylamine-based retinoids

Based on structure-activity relationship studies of the benzoic acid part of diphenylamine-based retinoids, the potent RXR agonist 4 was derivatized to obtain retinoid agonists, synergists, and an antagonist. Cinnamic acid derivatives 5 and phenylpropionic acid derivatives 6 showed retinoid agonistic and synergistic activities, respectively. The difference of the activities is considered to be due to differences in the flexibility of the carboxylic acid-containing substituent on the diphenylamine skeleton. Compound 7, bearing a methyl group at the meta position to the carboxyl group, was an antagonist, dose-dependently inhibiting HL-60 cell differentiation induced by 3.3 × 10-10 M Am80.