1416255-02-1

Basic information

• Product Name: C₂₈H₃₇NO₂
• CAS NO: 1416255-02-1
• Molecular Weight: 419.607
• Mol File: 1416255-02-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₇NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₇NO₂(1416255-02-1)
• EPA Substance Registry System: C₂₈H₃₇NO₂(1416255-02-1)

Safety Data

• Hazardous Substances Data: 1416255-02-1(Hazardous Substances Data)

Upstream product

• 1422445-95-1 C₂₅H₃₁NO₂ 
• 107-08-4 1-iodo-propane 
• 116233-17-1 3-methyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylamine 

Downstream Products

• 1416254-97-1 C₂₇H₃₇NO₂ 
• 1416254-92-6 C₂₇H₃₅NO₂ 

Relevant articles and documents

Structure-activity relationship study on benzoic acid part of diphenylamine-based retinoids

Based on structure-activity relationship studies of the benzoic acid part of diphenylamine-based retinoids, the potent RXR agonist 4 was derivatized to obtain retinoid agonists, synergists, and an antagonist. Cinnamic acid derivatives 5 and phenylpropionic acid derivatives 6 showed retinoid agonistic and synergistic activities, respectively. The difference of the activities is considered to be due to differences in the flexibility of the carboxylic acid-containing substituent on the diphenylamine skeleton. Compound 7, bearing a methyl group at the meta position to the carboxyl group, was an antagonist, dose-dependently inhibiting HL-60 cell differentiation induced by 3.3 × 10-10 M Am80.