141632-86-2

Upstream product

• 50-00-0 formaldehyd 
• 141632-85-1 (S)-N-(1-phenyleth-1-yl)-N-benzyloxycarbonylaminomethyl-acrylamide 
• 51440-81-4 3-benzyloxycarbonylaminobutyric acid 
• 501-53-1 benzyl chloroformate 
• 131968-96-2 (S,S,S)-1,3,5-tris(α-methylbenzyl)-1,3,5-hexahydrotriazine 
• 756495-07-5 (2-Chlorocarbonyl-1-methyl-ethyl)-carbamic acid benzyl ester 

Downstream Products

• 3775-73-3 (R)-3-aminobutanoic acid 
• 142055-30-9 (5R,6R)-5-Ethyl-6-methyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 
• 142055-31-0 (5S,6R)-5-Ethyl-6-methyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 
• 142055-32-1 (R)-5,5-Diethyl-6-methyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 
• 205534-22-1 (5R,6R)-5-Chloro-6-methyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 
• 205534-23-2 (5S,6R)-5-Chloro-6-methyl-4-oxo-3-((S)-1-phenyl-ethyl)-tetrahydro-pyrimidine-1-carboxylic acid benzyl ester 
• 205534-27-6 (1'S,2S,3R)-N-(1'-phenylethyl)-3-amino-2-chlorobutanamide 
• 205534-24-3 (2S,3R)-3-Methyl-aziridine-2-carboxylic acid ((S)-1-phenyl-ethyl)-amide 
• 205534-28-7 (2R,3R)-3-Methyl-aziridine-2-carboxylic acid ((S)-1-phenyl-ethyl)-amide 
• 205534-25-4 (2S,3R)-1-Acetyl-3-methyl-aziridine-2-carboxylic acid ((S)-1-phenyl-ethyl)-amide 
• 205534-29-8 (2R,3R)-1-Acetyl-3-methyl-aziridine-2-carboxylic acid ((S)-1-phenyl-ethyl)-amide 
• 205534-30-1 Acetic acid (1S,2R)-2-acetylamino-1-methyl-2-((S)-1-phenyl-ethylcarbamoyl)-ethyl ester 
• 205534-26-5 Acetic acid (1S,2S)-2-acetylamino-1-methyl-2-((S)-1-phenyl-ethylcarbamoyl)-ethyl ester 

Relevant academic research and scientific papers

Metal-Assisted Aldol Condensation of Chiral 6-Methyl Perihydropyrimidin-4-ones

The synthesis of 6-methyl perihydropyrimidin-4-ones (1'S,6R)-3a and (1'S,6S)-3b is reported starting from rac-3-aminobutanoic acid.The aldol condensation of various metal enolates of 3a and 3b with benzaldehyde and acetaldehyde is reported.All reactions a

USE OF CHIRAL AMIDALS IN THE SYNTHESIS OF 6-METHYLPERIHYDROPYRIMIDIN-4-ONES, PROTECTED FROM OF β-AMINO ACIDS

The synthesis of 6-methylperihydropyrimidin-4-ones (7a and 7b) is described by mercury cyclization of the β,γ-unsaturated amidal (3).After reduction of the intermediate organomercury compound (6) and separation of the diastereomeric mixture, the perihydropyrimidin-4-ones (7a and 7b) have been obtained.Their structure has been fully characterized by means of 1H NMR spectroscopy and, after acid hydrolysis, the 3-aminobutyric acids (8a and 8b) have been obtained.