1416323-12-0 Usage
Uses
Used in Pharmaceutical Industry:
N-methyl-1-(oxetan-3-yl)piperidin-4-amine is utilized as a building block for the synthesis of bioactive compounds due to its specific structure and properties. It contributes to the development of potential drug candidates, particularly in medicinal chemistry and drug discovery research.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-methyl-1-(oxetan-3-yl)piperidin-4-amine is employed as a key component in the design and synthesis of new pharmaceutical agents. Its reactivity and structural features facilitate the creation of compounds with desired therapeutic properties.
Used in Drug Discovery Research:
N-methyl-1-(oxetan-3-yl)piperidin-4-amine plays a significant role in drug discovery research, where it is used to explore and develop novel therapeutic agents. Its potential reactivity and unique structural elements make it a valuable tool in the search for new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 1416323-12-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,1,6,3,2 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1416323-12:
(9*1)+(8*4)+(7*1)+(6*6)+(5*3)+(4*2)+(3*3)+(2*1)+(1*2)=120
120 % 10 = 0
So 1416323-12-0 is a valid CAS Registry Number.
1416323-12-0Relevant articles and documents
Second basic pKa: An overlooked parameter in predicting phospholipidosis-inducing potential of diamines
Sakai, Hiroki,Inoue, Hidekazu,Murata, Kenji,Toba, Tetsuya,Takemoto, Naohiro,Matsumoto, Takahiro,Kawabata, Takeo
, (2020)
In this paper, we present the phospholipidosis-inducing potential (PLIP) of forty fragment-sized diamines derived from N-benzyl-4-(methylamino)piperidine and discuss the relationship between their PLIP and the physicochemical properties. Our results demonstrate that the previously reported methods are not suitable for predicting the PLIP of fragment-sized diamines; the second basic pKa can distinguish PLIP-positive diamines from PLIP-negative diamines more accurately than ClogP or most basic pKa. To the best of our knowledge, this is the first report describing the relationship between PLIP and second basic pKa.
