14165-68-5Relevant academic research and scientific papers
Synthesis, pharmacological profile and docking studies of new sulfonamides designed as phosphodiesterase-4 inhibitors
Da Costa Nunes, Isabelle Karine,De Souza, Everton Tenório,Cardozo, Suzana Vanessa S.,De Frias Carvalho, Vinicius,Romeiro, Nelilma Correia,Rodrigues E Silva, Patrícia Machado,Martins, Marco Aurélio,Barreiro, Eliezer J.,Lima, Lídia Moreira
, (2016)
Prior investigations showed that increased levels of cyclic AMP down-regulate lung inflammatory changes, stimulating the interest in phosphodiesterase (PDE)4 as therapeutic target. Here, we described the synthesis, pharmacological profile and docking prop
Synthesis, antioxidant, and antiacetylcholinesterase activities of sulfonamide derivatives of dopamine-related compounds
Goecer, Huelya,Akincioglu, Akin,Oeztaskin, Necla,Goeksu, Sueleyman,Guelcin, Ilhami
, p. 783 - 792 (2013)
A series of sulfonamides were synthesized from dopamine derivatives. The reactions of amines with methanesulfonyl chloride followed by O-demethylation with BBr3 afforded phenolic sulfonamides. The antioxidant activities of the synthesized pheno
Microwave-assisted synthesis of 1,2,3,4-tetrahydroisoquinoline sulfonamide derivatives and their biological evaluation
MANOLOV, STANIMIR P.,IVANOV, ILIYAN I.,BOJILOV, DIMITAR G.
, p. 139 - 151 (2021/03/22)
Herein we report an alternative eco-friendly method for the synthesis of 1,2,3,4-tetrahydroisoquinoline sulfonamide derivatives. All obtained compounds were screened for their in vitro inhibition of albumin denaturation, antioxidant, antitryptic and antib
