1416545-94-2

Upstream product

• 1416545-92-0 (1R,5R)-2-hydroxy-2-methyl-5-(prop-1-en-2-yl)cyclohex-3-enyl pivalate 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 84939-51-5 3,6,10-trimethyl-6,7,8,11-tetrahydro-4H-cyclodeca[b]furan-5-one 
• 81678-18-4 3,6,10-trimethyl-6,7,8,11-tetrahydro-4H-cyclodeca[b]furan-5-one 
• 1416545-98-6 (1R,2S,5S)-2-methyl-4-oxo-5-(2-methyloxiran-2-yl)-4-oxo-2-vinylcyclohexyl pivalate 
• 1427444-06-1 (1R,2R,5S)-2-methyl-4-oxo-5-(prop-1-en-2-yl)-2-vinylcyclohexyl pivalate 
• 1416545-96-4 (1R,2S,5S)-2-methyl-4-oxo-5-(prop-1-en-2-yl)-2-vinylcyclohexyl pivalate 

Relevant academic research and scientific papers

Non-natural elemane as the stepping stone for the synthesis of germacrane and guaiane sesquiterpenes

The synthesis of hydroxyelemane 5 from (R)-carvone and its utilization as a common synthetic scaffold to produce structurally diverse germacrane and guaiane sesquiterpenes are described. A highly enantio- and stereoselective biomimetic tandem oxy-Cope/ene rearrangement was used as the key reaction to access the 10-membered macrocyclic core of germacranes and the condensed 5-7 carbocycles of guaiane sesquiterpenes. Additionally, reactions of furanoguaianes under acidic or oxidizing reagents have been investigated, and preliminary results of these conversions are presented.