1416721-24-8 Usage
Description
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzaldehyde is a complex organic chemical compound that features a benzaldehyde group, a boron-containing moiety, and a trifluoromethyl group. 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzaldehyde is integral to organic synthesis and chemical research, particularly in the formation of carbon-carbon bonds and as a reagent in the Suzuki coupling reaction. Its unique structure, which includes a tetramethyl-1,3,2-dioxaborolan-2-yl group, enhances its reactivity and applicability in cross-coupling reactions, making it a valuable component in the development of pharmaceuticals, agrochemicals, and materials science.
Uses
Used in Organic Synthesis:
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzaldehyde is used as a key intermediate in organic synthesis for the creation of complex organic molecules. Its benzaldehyde group and boron-containing moiety facilitate the formation of carbon-carbon bonds, which are essential in constructing the backbones of various organic compounds.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzaldehyde is used as a building block for the synthesis of new drug candidates. The presence of the trifluoromethyl group is particularly advantageous, as it can impart specific biological activities and properties to the resulting compounds, making them potential candidates for the treatment of various diseases.
Used in Agrochemicals:
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzaldehyde is also utilized in the agrochemical sector as a precursor for the development of new pesticides and herbicides. The trifluoromethyl group can enhance the effectiveness and selectivity of these compounds, leading to improved crop protection.
Used in Materials Science:
In materials science, 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzaldehyde is used as a component in the synthesis of advanced materials with unique properties. Its ability to participate in cross-coupling reactions allows for the creation of new materials with tailored characteristics for specific applications, such as in electronics or as high-performance polymers.
It is important to handle 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)benzaldehyde with care due to its potential health and environmental risks if not properly managed. Proper safety measures and disposal methods should be adhered to when working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 1416721-24-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,1,6,7,2 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1416721-24:
(9*1)+(8*4)+(7*1)+(6*6)+(5*7)+(4*2)+(3*1)+(2*2)+(1*4)=138
138 % 10 = 8
So 1416721-24-8 is a valid CAS Registry Number.
1416721-24-8Relevant articles and documents
PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME
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Paragraph 0353; 0356; 0357; 0372; 0373; 0374, (2019/07/15)
Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
Formal Ir-Catalyzed Ligand-Enabled Ortho and Meta Borylation of Aromatic Aldehydes via in Situ-Generated Imines
Bisht, Ranjana,Chattopadhyay, Buddhadeb
supporting information, p. 84 - 87 (2016/01/25)
The ligand-enabled development of ortho and meta C-H borylation of aromatic aldehydes is reported. It was envisaged that while ortho borylation could be achieved using tert-butylamine as the traceless protecting/directing group, meta borylation proceeds via an electrostatic interaction and a secondary interaction between the ligand of the catalyst and the substrate. These ligand-substrate electrostatic interactions and secondary B-N interactions provide an unprecedented controlling factor for meta-selective C-H activation/borylation.
