1416896-95-1

Basic information

• Product Name: (2E,5E)-2,5-bis(4-(3-morpholinopropoxy)benzylidene)cyclopentanone
• Synonyms: (2E,5E)-2,5-bis(4-(3-morpholinopropoxy)benzylidene)cyclopentanone
• CAS NO: 1416896-95-1
• Molecular Weight: 546.707
• Mol File: 1416896-95-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2E,5E)-2,5-bis(4-(3-morpholinopropoxy)benzylidene)cyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2E,5E)-2,5-bis(4-(3-morpholinopropoxy)benzylidene)cyclopentanone(1416896-95-1)
• EPA Substance Registry System: (2E,5E)-2,5-bis(4-(3-morpholinopropoxy)benzylidene)cyclopentanone(1416896-95-1)

Safety Data

• Hazardous Substances Data: 1416896-95-1(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 71760-44-6 4-(3-morpholin-4-ylpropoxy)benzaldehyde 
• 120-92-3 cyclopentanone 
• 17954-81-3 4-(3-bromopropoxy)benzaldehyde 

Relevant articles and documents

Synthesis, antimalarial activity and cytotoxic potential of new monocarbonyl analogues of curcumin

A series of novel monocarbonyl analogues of curcumin have been designed, synthesized and tested for their activity against Molt4, HeLa, PC3, DU145 and KB cancer cell lines. Six of the analogues showed potent cytotoxicity towards these cell lines with IC50 values below 1 μM, which is better than doxorubicin, a US FDA approved drug. Several analogues were also found to be active against both CQ-resistant (W2 clone) and CQ-sensitive (D6) strains of Plasmodium falciparum in an in-vitro antimalarial screening. This level of activity warrants further investigation of the compounds for development as anticancer and antimalarial agents.