1416907-70-4

Basic information

• Product Name: (S)-1-(4-chloro-phenyl)-2-{4-[1-hydroxy-1-(3-methoxy-phenyl)-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one
• CAS NO: 1416907-70-4
• Molecular Weight: 572.101
• Mol File: 1416907-70-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-(4-chloro-phenyl)-2-{4-[1-hydroxy-1-(3-methoxy-phenyl)-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(4-chloro-phenyl)-2-{4-[1-hydroxy-1-(3-methoxy-phenyl)-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one(1416907-70-4)
• EPA Substance Registry System: (S)-1-(4-chloro-phenyl)-2-{4-[1-hydroxy-1-(3-methoxy-phenyl)-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one(1416907-70-4)

Safety Data

• Hazardous Substances Data: 1416907-70-4(Hazardous Substances Data)

Upstream product

• 1313365-55-7 (4-isopropoxy-5-methoxy-2-{[(E)-(S)-2-methyl-propane-2-sulfinylimino]-methyl}-phenyl)-acetic acid ethyl ester 
• 1313365-56-8 {2-[(S)-(4-chloro-phenyl)-((S)-2-methyl-propane-2-sulfinylamino)-methyl]-4-isopropoxy-5-methoxy-phenyl}-acetic acid ethyl ester 
• 1313365-54-6 (2-formyl-4-isopropoxy-5-methoxy-phenyl)-acetic acid ethyl ester 
• 1256581-66-4 (4-isopropoxy-3-methoxy-phenyl)-acetic acid ethyl ester 
• 60563-13-5 ethyl homovanillate 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 13329-40-3 4-Iodoacetophenone 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 14064-15-4 (4-chlorophenyl)trimethylstannane 

Relevant articles and documents

HYDROXY SUBSTITUTED ISOQUINOLINONE DERIVATIVES

The invention relates to compounds of formula (I): as defined in the application. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.