1416975-71-7Relevant articles and documents
Heat-or light-induced acylarylation of unactivated alkenes towards 3-(α-acyl) indolines
Dong, Ying,Fu, Tingfeng,Han, Yinghui,Li, Yanni,Liang, Deqiang,Lin, Liqing,Long, Xianhao,Yang, Ruihan,Ying, Fengyuan
, p. 5660 - 5665 (2020)
A heat-or photoredox/iron dual catalysis-enabled dehydrogenative acylarylation of N-allyl anilines leading to 2-substituted 3-(α-acyl) indolines with a quaternary stereogenic center is presented, with unactivated alkenic bonds as radical acceptors and simple aldehydes as radical precursors. This reaction features high yields, a broad substrate scope, and a great exo selectivity, and gram-scale syntheses could be readily carried out.
Synthesis of difluoromethylselenoesters from aldehydes: Via a radical process
Guo, Rui-Li,Zhu, Xue-Qing,Zhang, Xing-Long,Wang, Yong-Qiang
, p. 8976 - 8979 (2020)
Difluoromethylselenoester compounds, another important kind of organoselenium compounds, are reported herein for the first time. They can be efficiently synthesized from aldehydes and BnSeCF2H. The synthetic method features mild reaction conditions, broad substrate scope, good tolerance of functional groups, and importantly, no metal is involved in the reaction.
Microwave-Accelerated N-Acylation of Sulfoximines with Aldehydes under Catalyst-Free Conditions
Ambala, Srinivas,Arvidsson, Per I.,Govender, Thavendran,Kruger, Hendrik G.,Naicker, Tricia,Rajbongshi, Kamal K.
, p. 1279 - 1286 (2020/04/15)
An efficient catalyst-free radical cross-coupling reaction between aromatic aldehydes and sulfoximines was developed. The reaction took place in the presence of N-bromosuccinimide as the radical initiator under microwave irradiation to afford the corresponding acylated sulfoximines in moderate to excellent yields (27 examples). This protocol proved to be rapid, easy to handle, and applicable to a broad scope of substrates.
