141708-75-0Relevant academic research and scientific papers
Synthesis of 3-gem-difluoro-2-ethoxy allylic alcohols from ethyl chlorodifluoroacetate
Begue, Jean-Pierre,Bonnet-Delpon, Daniele,Rock, Michael H.
, p. 6097 - 6100 (2007/10/02)
The chlorine atom in chlorodifluoromethyl epoxy ethers is unusually reactive towards butyllithium. This reactivity has been used to develop a concise synthesis of gem-difluoro-2-ethoxy allylic alcohols from the commercially available ethylchlorodifluoroacetate.
