1417159-45-5

Upstream product

• 1417159-42-2 methyl (5S,8S,11S)-5-(4-azidobutyl)-8-isobutyl-3,6,9-trioxo-1-phenyl-11-(prop-2-yn-1-yl)-2-oxa-4,7,10-triazadodecan-12-oate 
• 101925-55-7 (S)-propargylglycine methyl ester 
• 1359969-70-2 (S)-2-((S)-6-azido-2-(((benzyloxy)carbonyl)amino)hexanamido)-4-methylpentanoic acid 

Downstream Products

• 1417159-46-6 benzyl ((6S,9S,12S)-12-(hydroxymethyl)-9-isobutyl-7,10-dioxo-1,8,11,15,16-pentaazabicyclo[12.2.1]heptadeca-14⁽¹⁷⁾,15-dien-6-yl)carbamate 

Relevant academic research and scientific papers

New cylindrical peptide assemblies defined by extended parallel β-sheets

A new approach to non-covalent peptide-based nanotubular or rod-like structures is presented, whereby the monomeric units are preorganised into a β-strand geometry that templates the formation of an extended and unusual parallel β-sheet rod-like structure. The conformational constraint is introduced by Huisgen cycloaddition to give a triazole-based macrocycle, with the resulting self-assembled structures stabilized by a well-defined series of intermolecular hydrogen bonds. The Royal Society of Chemistry 2013.