14174-93-7 Usage
Uses
Used in Pharmaceutical Industry:
(3Z)-3-(ethoxy-hydroxy-methylidene)isoquinoline-1,4-dione is used as a drug candidate for its demonstrated anticancer properties, making it a potential agent in the development of new cancer treatments. Its antimicrobial activity also suggests its potential use in the creation of new antimicrobial drugs to combat resistant infections.
Used in Organic Synthesis:
In the field of organic synthesis, (3Z)-3-(ethoxy-hydroxy-methylidene)isoquinoline-1,4-dione serves as a valuable intermediate or building block for the synthesis of more complex organic compounds, including those with potential pharmaceutical applications. Its unique structural features contribute to the diversity of chemical libraries and the discovery of new bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 14174-93-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,1,7 and 4 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 14174-93:
(7*1)+(6*4)+(5*1)+(4*7)+(3*4)+(2*9)+(1*3)=97
97 % 10 = 7
So 14174-93-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO4/c1-2-17-12(16)9-10(14)7-5-3-4-6-8(7)11(15)13-9/h3-6,14H,2H2,1H3,(H,13,15)
14174-93-7Relevant academic research and scientific papers
Mittendorf, Fabia,Mohr, Fabian,Kirsch, Stefan F.
, p. 12760 - 12769 (2020)
A novel ring expansion based on the readily available 2-azido-2-phenyl-indan-1,3-dione is described. Treatment with primary amines and cesium carbonate in a two-step sequence gives rise to 3-amino-2,3-dihydroisoquinoline-1,4-diones with an unprecedented substitution pattern. The corresponding conversion using amino acid methyl esters leads directly to a novel tricyclic 1,10a-dihydroimidazo-isoquinoline-2,5,10-trione scaffold, a structure that has never been reported before, to the best of our knowledge.
4-Hydroxy-1(2H)-isoquinolone-3-carboxamides. Synthesis and Properties
Schapira, Celia B.,Abasolo, Maria I.,Perillo, Isabel A.
, p. 577 - 581 (2007/10/02)
Reaction of some α-phthalimidoacetamides 1a-i with sodium ethoxide was carried out under drastic conditions.Compounds 1b-g afforded 4-hydroxy-1(2H)-isoquinolone-3-carboxamides 2b-g, while 1h-i afforded the acids 3a-b together with the expected isoquinolon
