1417418-40-6Relevant articles and documents
Thiol-inducible direct fluorescence monitoring of drug release
Wu, Jun,Huang, Rong,Wang, Changcheng,Liu, Wenting,Wang, Jiaqi,Weng, Xiaocheng,Tian, Tian,Zhou, Xiang
, p. 580 - 585 (2013)
A new bifunctional compound NCC, which undergoes thiol-mediated disulfide cleavage after cell entry, produces a red-shifted fluorescent emission in the cytosol and releases free active DNA alkylating agent CLB into the nucleus, and finally leads to DNA damage and cell death.