141765-48-2Relevant academic research and scientific papers
Electrophilic Substitution of a 2-Azabicyclohept-5-en-3-one as a Potential Route to 3-Deoxycarbocyclic Nucleosides
Palmer, Christopher F.,Parry, Keith P.,Roberts, Stanley M.
, p. 484 - 486 (1991)
The γ-lactam 9 reacted with bromine in the presence of acetic acid or fluoride ion to give the 6,7-substituted 2-azanorbornan-3-ones 10 or 15 respectively.The latter compounds were converted into the cyclopentylamine derivatives 14 and 16 which represent
Rearrangement of 2-Azabicyclohept-5-en-3-ones: Synthesis of cis-3-Aminocyclopentane Carboxylic Acid Derivatives
Palmer, Christopher F.,Parry, Keith P.,Roberts, Stanley M.,Sik, Vladimir
, p. 1021 - 1028 (2007/10/02)
The γ-lactam 4 was converted into the bromo ester 6 and the latter compound was transformed in five steps into the diester 10.Similarly the lactam 4 was converted into the hydroxy amide 17 via the intermediacy of the dihalogeno compound 11.Compounds 10 an
