1417729-28-2

Basic information

• Product Name: 1,4-bis(4-methoxybenzyloxycarbonyl)-7-(tert-butylcarbonate)-1,4,7-triazacyclononane
• Synonyms: 1,4-bis(4-methoxybenzyloxycarbonyl)-7-(tert-butylcarbonate)-1,4,7-triazacyclononane
• CAS NO: 1417729-28-2
• Molecular Weight: 557.644
• Mol File: 1417729-28-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,4-bis(4-methoxybenzyloxycarbonyl)-7-(tert-butylcarbonate)-1,4,7-triazacyclononane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis(4-methoxybenzyloxycarbonyl)-7-(tert-butylcarbonate)-1,4,7-triazacyclononane(1417729-28-2)
• EPA Substance Registry System: 1,4-bis(4-methoxybenzyloxycarbonyl)-7-(tert-butylcarbonate)-1,4,7-triazacyclononane(1417729-28-2)

Safety Data

• Hazardous Substances Data: 1417729-28-2(Hazardous Substances Data)

Upstream product

• 59577-32-1 2-(4-methoxybenzyloxycarbonyloxyimino)-2-phenylacetonitrile 
• 13139-12-3 tert-butyl 2,5-dioxopyrrolidin-1-yl carbonate 
• 1417729-26-0 1,4-bis(4-methoxybenzyloxycarbonyl)-1,4,7-triazacyclononane 
• 58966-93-1 1,4,7-triazacyclononane trihydrochloride 

Relevant articles and documents

NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES

The invention relates to complexing agents of formula (I): in which A, chrom1, chrom2 and chrom3 are as defined in the description. The invention also relates to the lanthanide complexes obtained from these complexing agents.

Bright mono-aqua europium complexes based on triazacyclononane that bind anions reversibly and permeate cells efficiently

A series of five europium(III) complexes has been prepared from heptadentate N5O2 ligands that possess a brightness of more than 10 mM-1 cm-1 in water, following excitation over the range λ=330-355 nm. Binding of several oxy anions has been assessed by emission spectral titrimetric analysis, with the binding of simple carboxylates, lactate and citrate involving a common ligation mode following displacement of the coordinated water. Selectivity for bicarbonate allows the rapid determination of this anion in human serum, with Kd=37 mM (295 K). The complexes are internalised quickly into mammalian cells and exhibit a mitochondrial localisation at early time points, migrating after a few hours to reveal a predominant lysosomal distribution. Herein, we report the synthesis and complexation behaviour of strongly emissive europium (III) complexes that bind oxy-anions in aqueous media with an affinity and selectivity profile that is distinctively different from previously studied systems. Let there be light! A new class of luminescent anion-responsive europium complexes, which enter mammalian cells and accumulate in the lysosomes, has been synthesized. Each EuIII complex is based on a triazacyclononane core with two alkynyl-aryl sensitizers and one coordinated water molecule (see figure). Copyright