141807-25-2Relevant academic research and scientific papers
A Novel Synthetic Method of Glifolin derivative and Pharmaceutical Composition for Treatment and Prevention of Hyperlipidemia Comprising the Same as an Active Ingredient
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Paragraph 0017; 0018; 0025, (2018/08/25)
The present invention relates to a novel method for synthesizing an SPC-47 compound as a glifolin derivative, and a pharmaceutical composition for preventing and treating hyperlipidemia containing the same as an active ingredient. The novel compound exhib
Directed ortho-Metalation of Aryl Amides, O-Carbamates, and Methoxymethoxy Systems: Directed Metalation Group Competition and Cooperation
Miah, M. A. Jalil,Sibi, Mukund P.,Chattopadhyay,Familoni, Oluwole B.,Snieckus, Victor
supporting information, p. 447 - 454 (2017/12/15)
A systematic study on the competitive metalation of derivatives containing four directed metalation groups (DMGs), namely, Cl, OMe, methoxymethoxy (OMOM), and CONEt2, in comparison with the OCONEt2 DMG is described. In addition, the
Directed ortho metalation reactions of aryl O-carbamates; a regiospecific synthesis of 2,2-disubstituted 2H-1-benzopyrans
Chauder,Kalinin,Snieckus
, p. 140 - 144 (2007/10/03)
A one-pot regiocontrolled synthesis of 2,2-disubstituted 2H-1-benzopyrans 5 from aryl O-carbamates 4 using the directed ortho metalation reaction is described and constitutes an advantageous complement to classical routes for this class of heterocycles.
