1418104-69-4

Basic information

• Product Name: C₁₅H₁₅ClN₂O₄S
• Synonyms: C₁₅H₁₅ClN₂O₄S
• CAS NO: 1418104-69-4
• Molecular Weight: 354.814
• Mol File: 1418104-69-4.mol

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₅ClN₂O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₅ClN₂O₄S(1418104-69-4)
• EPA Substance Registry System: C₁₅H₁₅ClN₂O₄S(1418104-69-4)

Safety Data

• Hazardous Substances Data: 1418104-69-4(Hazardous Substances Data)

Upstream product

• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 22264-49-9 spiro[bicyclo[2.2.1]heptane-2',5'-imidazolidine[2,4]dione] 
• 497-38-1 Norbornan-2-on 

Relevant articles and documents

Dual action spirobicycloimidazolidine-2,4-diones: Antidiabetic agents and inhibitors of aldose reductase-an enzyme involved in diabetic complications

The desired 3-(arylsulfonyl)spiroimidazolidine-2,4-diones were synthesized by reacting spiroiminoimidazolidine-2,4-dione with arylsulfonyl chlorides. Spiroimidazolidine-2,4-dione was in turn synthesized from norcamphor. Structures of the synthesized molecules were established by modern spectroscopic techniques. The synthesized compounds were screened for in vivo antidiabetic activity and aldose reductase inhibition. Compounds 2a, 2b and 2g exhibited excellent dual activity, compound 2a being most prominent. These results reveal that the synthesized compounds may serve as the molecule of choice to treat diabetes and diabetic complications using a single medication.