1418117-80-2

Usage

Uses

Used in Pharmaceutical Research and Development:
3-Bromo-4-(chloromethyl)pyridine hydrochloride is used as a reagent in the synthesis of pharmaceuticals for its ability to undergo substitution reactions. It serves as a valuable building block in the preparation of various compounds, contributing to the development of new drugs and novel chemical materials.
Used in Agrochemical Synthesis:
In the agrochemical industry, 3-Bromo-4-(chloromethyl)pyridine hydrochloride is used as a reagent in the synthesis of agrochemicals. Its ability to participate in substitution reactions allows for the creation of compounds that can be used in the development of pesticides, herbicides, and other agricultural chemicals to improve crop protection and yield.
Used in Organic Synthesis:
3-Bromo-4-(chloromethyl)pyridine hydrochloride is utilized in organic synthesis as a versatile intermediate. Its reactivity in substitution reactions makes it suitable for the preparation of a wide range of organic compounds, which can be further used in various applications across different industries, including pharmaceuticals, agrochemicals, and materials science.

Upstream product

• 146679-66-5 3-bromo-4-(hydroxymethyl)pyridine 
• 70201-43-3 3-bromo-pyridine-4-carbaldehyde 

Downstream Products

• 1620644-81-6 1-benzyl-4-(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl) methyl-1,4-dihydropyridine-3-acetyl 
• 1620644-79-2 1-benzyl-3-acetyl-4-(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl) methyl pyridinium bromide 
• 1620644-73-6 1-benzyl-3-bromo-4-(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methylpyridinium iodide 
• 1620644-71-4 1-benzyl-4-((5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2 yl)methyl)pyridinium iodide 

Relevant academic research and scientific papers

OXIDISABLE PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTI-ALZHEIMER AGENTS

A compound of formula (I) in which the dotted lines indicate the presence of at least one double bond; n = 0 to 4; R3 and R4 are H, or when n = 1, R3 and R4 can also form together a double bond between the carbon atoms, and m = 0, 1 or 2, Z is CH or N or Z is C and - CHR3- is =CH- linked by the double bond to cyclopentanone; or - (-)m- is absent, and Z is NH, >N-alkyl, >N-phenyl, >N-benzyl or >N heteroaryl; R8 is alkyl, aryl or heteroaryl which can be optionally substituted; EWG represents an electron withdrawing group selected from the group comprising COOR, COSR, CONRR', CN, COR, CF3, SOR, SO2R, SONRR', SO2NRR', NO2, halogen, heteroaryl; and the pharmaceutical salts and stereisomers thereof. The compounds of formula (I) are potent in the treatment of neurodegenerative diseases such as Alzheimer's disease.

Oxidisable pyridine derivatives, their preparation and use as anti-Alzheimer agents

A compound of the formula (I) in which the dotted lines indicate the presence of at least one double bond; n = 0 to 4; R3 and R4 are H, or when n = 1, R3 and R4 can also form together a double bond between the carbon atoms, and m = 0, 1 or 2, Z is CH or N or Z is C and -CHR3- is =CH- linked by the double bond to the cyclopentanone; or -(-)m- is absent, and Z is NH, >N-alkyl, >N-phenyl, >N-benzyl or >N-heteroaryl; R8 is alkyl, aryl or heteroaryl which can be optionally substituted; EWG represents an electron withdrawing group selected from the group comprising COOR, COSR, CONRR', CN, COR, CF3, SOR, SO2R, SONRR', SO2NRR', NO2, halogen, heteroaryl; and the pharmaceutical salts or tautomers thereof. The compounds of formula (I) are potent in the treatment of neurodegenerative diseases such as Alzheimer's disease.