141815-42-1

Basic information

• Product Name: C-(4-PYRIDIN-2-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE
• Synonyms: C-(4-PYRIDIN-2-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE;(4-(Pyridin-2-ylMethyl)Morpholin-2-yl)MethanaMine trihydrochloride;[4-(pyridin-2-ylmethyl)morpholin-2-yl]methanamine
• CAS NO: 141815-42-1
• Molecular Formula: C11H20Cl3N3O
• Molecular Weight: 316.655
• Mol File: 141815-42-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: C-(4-PYRIDIN-2-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: C-(4-PYRIDIN-2-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE(141815-42-1)
• EPA Substance Registry System: C-(4-PYRIDIN-2-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE(141815-42-1)

Safety Data

• Hazardous Substances Data: 141815-42-1(Hazardous Substances Data)

Usage

General Description

C-(4-PYRIDIN-2-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE is a chemical compound with a complex structure that includes a morpholine ring and a pyridine moiety. The presence of a trihydrochloride salt indicates that the compound has three chloride ions associated with it. This chemical may be used in research or industrial applications, and its specific properties and uses would depend on the context and intended purpose. For example, it might be used as a building block in the synthesis of pharmaceuticals or other organic compounds. As with any chemical, appropriate precautions should be taken when handling C-(4-PYRIDIN-2-YLMETHYL-MORPHOLIN-2-YL)-METHYLAMINE TRIHYDROCHLORIDE to ensure safety and proper storage.

Upstream product

• 112913-95-8 2-(N-acetylaminomethyl)morpholine 
• 112913-96-9 2-(N-acetylaminomethyl)-4-benzylmorpholine 
• 112886-84-7 N-(4-Pyridin-2-ylmethyl-morpholin-2-ylmethyl)-acetamide 

Relevant articles and documents

Novel benzamides as selective and potent gastrokinetic agents. III. Synthesis and structure-activity relationships of 4-amino-5-chloro-2-methoxy- and 2-ethoxy-N-[(4-substituted 2-morpholinyl)methyl]-benzamides

A series of 4-amino-5-chloro-2-methoxy- and 2-ethoxy-N-[(4-substituted 2-morpholinyl)methyl]benzamides (11-44) were prepared and evaluated for gastrokinetic activity by determining their effects on the gastric emptying of phenol red semisolid meal in rats. The N-4 substituent includes alkyl, phenoxyalkyl, (4-fluorobenzoyl)alkyl, and heteroarylmethyl groups. The benzamide derivatives, having an isopropyl, isoamyl, neopentyl, 3-(4-chlorophenoxy)propyl, or pyridylmethyl group at N-4, showed potent in vivo gastric emptying activity. In particular, 4-amino-5-chloro-2-ethoxy-N-[[4-(3-pyridylmethyl)-2-morpholinyl]methyl ]benzamide (57b) was equipotent to the 4-fluorobenzyl analogue 1b (AS-4370 as its citrate) in the gastrokinetic activity on phenol red semisolid meal in rats and mice, and on resin pellet solid meal in rats. Moreover, compound 57b was free from dopamine D2 receptor antagonistic activity in both in vitro ([3H]spiperone binding) and in vivo (apomorphine-induced emesis in dogs) tests. Structure-activity relationships of compounds with various substituents at N-4 are also discussed.