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141819-07-0

(diselanediylbis(1,2-phenylene))dimethanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 141819-07-0 Structure

  • Basic information

    1. Product Name: (diselanediylbis(1,2-phenylene))dimethanol
    2. Synonyms: (diselanediylbis(1,2-phenylene))dimethanol
    3. CAS NO:141819-07-0
    4. Molecular Formula:
    5. Molecular Weight: 372.184
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 141819-07-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (diselanediylbis(1,2-phenylene))dimethanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: (diselanediylbis(1,2-phenylene))dimethanol(141819-07-0)
    11. EPA Substance Registry System: (diselanediylbis(1,2-phenylene))dimethanol(141819-07-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 141819-07-0(Hazardous Substances Data)

141819-07-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 141819-07-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,8,1 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 141819-07:
(8*1)+(7*4)+(6*1)+(5*8)+(4*1)+(3*9)+(2*0)+(1*7)=120
120 % 10 = 0
So 141819-07-0 is a valid CAS Registry Number.

141819-07-0Relevant articles and documents

Diselenides and benzisoselenazolones as antiproliferative agents and glutathione-S-transferase inhibitors

Krasowska, Dorota,Iraci, Nunzio,Santi, Claudio,Drabowicz, Józef,Cieslak, Marcin,Ka?mierczak-Barańska, Julia,Palomba, Martina,Królewska-Golińska, Karolina,Magiera, Jakub,Sancineto, Luca

, (2019/08/20)

A series of variously functionalized selenium-containing compounds were purposely synthesized and evaluated against a panel of cancer cell lines. Most of the compounds showed an interesting cytotoxicity profile with compound 5 showing a potent activity on MCF7 cells. The ethyl amino derivative 5 acts synergistically with cis-platin and inhibits the GST enzyme with a potency that well correlates with the cytotoxicity observed in MCF7 cells. A computational analysis suggests a possible binding mode on the GST enzyme. As the main outcome of the present study, the ethyl amino derivative 5 emerged as a valid lead compound for further, future developments.

An investigation of in vitro cytotoxicity and apoptotic potential of aromatic diselenides

Rizvi, Masood Ahmad,Guru, Santosh,Naqvi, Tahira,Kumar, Manjeet,Kumbhar, Navanath,Akhoon, Showkat,Banday, Shazia,Singh, Shashank K.,Bhushan, Shashi,Mustafa Peerzada,Shah, Bhahwal Ali

, p. 3440 - 3446 (2014/07/22)

A target synthesis of a library of symmetric aromatic diselenides was attempted with the aim of generating anticancer lead compounds. Out of thirteen screened molecules (1-13) against a panel of human cancer cell lines, compound 8 exhibited highest cell growth inhibition in Human leukemia HL-60 cells with IC50 value of 8 μM. Compound 8 had a good pro-apoptotic potential as evidenced from several apoptotic protocols like DNA cell cycle analysis and monitoring of apoptotic bodies formation using phase contrast and nuclear microscopy with Hoechst 33,258. Also, 8 significantly inhibits S phase of the cell cycle and eventually trigger apoptosis in HL-60 cells through mitochondrial dependent pathway substantiated by the loss of mitochondrial potential. A theoretical investigation of DNA binding ability of 8 showed that it selectively bind to minor groove of DNA, where it is stabilized by hydrogen bonding and hydrophobic interactions.

o-hydroxylmethylphenylchalcogens: Synthesis, intramolecular nonbonded chalcogen...OH interactions, and glutathione peroxidase-like activity

Tripathi, Santosh K.,Patel, Upali,Roy, Dipankar,Sunoj, Raghavan B.,Singh, Harkesh B.,Wolmershaeuser, Gotthelf,Butcher, Ray J.

, p. 9237 - 9247 (2007/10/03)

The synthesis and characterization of a series of organochalcogen (Se, Te) compounds derived from benzyl alcohol 13 are described. The synthesis of the key precursor dichalcogenides 15, 22, and 29 was achieved by the ortho-lithiation route. Selenide 18 wa

DIRECT OBSERVATION OF INTRAMOLECULAR INTERACTION BETWEEN A DIVALENT SELENIUM AND A TERTIARY AMINE BY MEANS OF SINGLE CRYSTAL X-RAY ANALYSIS AND NMR SPECTROSCOPY

Iwaoka, Michio,Tomoda, Shuji

, p. 125 - 130 (2007/10/02)

Intramolecular interaction between a divalent selenium and a tertiary amino moiety has been observed in the solid state for 2,2'-diselenobis(N-cyclohexyl-N-methylbenzyl amine)(1).A similar interaction between an electrophilic selenium and a tertiary amine

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